Sun Exposure & Skin Cancer
Many people love the
sun. The sun's rays make us feel good, and in the short term, it makes us look
good. But our love affair isn't a two-way street: Exposure to sun causes most
of the wrinkles and age spots on our faces. Consider this: One woman at age 40
who has protected her skin from the sun actually has the skin of a 30-year-old.
We
often associate a glowing complexion with good health, but skin color obtained
from being in the sun can actually mean accelerated effects of aging and an
increased risk for developing skin cancer.
Sun
exposure causes most of the skin changes that we think of as a normal part of
aging. Over time, the sun's ultraviolet (UV) light damages the fibers in the
skin called elastin. When these
fibers breakdown, the skin begins to sag, stretch, and lose its ability to go
back into place after stretching. The skin also bruises and tears more easily
in addition to taking longer to heal. So while sun damage to the skin may not
be apparent when you're young, it will definitely show later in life.
Changes in the skin
related to sun exposure:
·
Precancerous (actinic keratosis)
and cancerous (basal cell carcinoma, squamous cell carcinoma, and melanoma) skin
lesions caused by loss of the skin's immune function
·
Benign tumors
·
Fine and coarse wrinkles
·
Freckles
·
Discolored areas of
the skin, called mottled pigmentation
·
Sallowness: a yellow
discoloration of the skin
·
Telangiectasias: the
dilation of small blood vessels under the skin
·
Elastosis: the
destruction of the elastic tissue causing lines and wrinkles
What is skin cancer?
Skin cancer is the
most prevalent form of all cancers in the US, and the number of cases continues
to rise. It is the uncontrolled growth of abnormal skin cells. While healthy
cells grow and divide in an orderly way, cancer cells grow and divide in a
rapid, haphazard manner. This rapid growth results in tumors that are either
benign (noncancerous) or malignant (cancerous).
There are three main
types of skin cancer:
·
Basal cell carcinoma
·
Squamous cell
carcinoma
·
Melanoma
Basal cell and
squamous cell cancers are less serious types and make up 95% of all skin
cancers. Also referred to as non-melanoma skin cancers, they are highly curable
when treated early.
Melanoma, made up of
abnormal skin pigment cells called melanocytes, is the most serious form of
skin cancer and causes 75% of all skin cancer deaths. Left untreated, it can
spread to other organs and is difficult to control.
What causes skin cancer?
Ultraviolet (UV)
radiation from the sun is the number one cause of skin cancer, but UV light
from tanning beds is just as harmful. Exposure to sunlight during the winter
months puts you at the same risk as exposure during the summertime.
Cumulative sun
exposure causes mainly basal cell and squamous cell skin cancer, while episodes
of severe blistering sunburns, usually before age 18, can cause melanoma later
in life. Other less common causes are repeated X-ray exposure, scars from burns
or disease, and occupational exposure to certain chemicals.
Who is at risk for skin cancer?
Although anyone can
get skin cancer, the risk is greatest for people who have fair or freckled skin
that burns easily, light eyes and blond or red hair. Darker-skinned individuals
are also susceptible to all types of skin cancer, although their risk is lower.
Aside
from complexion, other risk factors include having a family history or
personal history of skin cancer, having an outdoor job, and living in a sunny
climate. A history of severe sunburns and an abundance of large and irregularly
shaped moles are risk factors unique to melanoma.
What are the signs and symptoms of skin cancer?
The
most common warning sign of skin cancer is a change on the skin, typically a
new mole or skin
lesion or a change in an existing mole.
·
Basal cell carcinoma
may appear as a small, smooth, pearly, or waxy bump on the face ears and neck;
or as a flat, pink/red- or brown-colored lesion on the trunk or arms and legs.
·
Squamous cell
carcinoma can appear as a firm, red nodule, or as a rough, scaly flat lesion
that may itch, bleed, and become crusty. Both basal cell and squamous cell
cancers mainly occur on areas of the skin frequently exposed to the sun, but
can occur anywhere.
·
Melanoma usually
appears as a pigmented patch or bump. It may resemble a normal mole, but
usually has a more irregular appearance.
When looking for melanoma,
think of the ABCD rule that tells you the signs to watch for:
·
Asymmetry: the shape
of one half doesn't match the other
·
Border: edges are
ragged or blurred
·
Color: uneven shades
of brown, black, tan, red, white, or blue
·
Diameter: a
significant change in size (greater than 6 mm)
How is it diagnosed?
Skin
cancer is suspected by its appearance on the skin. The diagnosis must be
confirmed with abiopsy. This
involves taking a sample of the tissue, which is then placed under a microscope
and examined by a dermatopathologist, a doctor who specializes in examining
skin cells. Sometimes a biopsy can remove all of the cancer tissue and no
further treatment is needed.
Sunlight causes your
skin to produce vitamin D -- a fact that, ironically, means that sunscreen
campaigns may have made millions of people chronically short of this
critical nutrient, and put them at a greater risk of skin cancer, rather than reducing
their risk.
Research shows that a
very low level of vitamin D is a major risk factor for melanoma. This
flies in the face of the idea that it is too much sun that increases your
melanoma risk.
There is convincing evidence that sunlight
causes skin cancer. Skin cancer can be treated and cured without serious
consequences. However, in some cases the condition can be life-threatening if
not diagnosed in time.
Skin cancer is an occupational concern for
people who work under the sun. The risk however, may be reduced through
awareness of the problem, and by taking measures to prevent exposure to
sunlight.
Yes. The types of radiation include
·
visible light, which
gives us the colours we see
·
infrared radiation
which gives us the warmth we feel
·
ultraviolet (UV)
radiation
Except in extreme situations, neither visible
light nor infrared radiation from sunlight causes health problems. However,
ultraviolet (UV) radiation can cause harmful effects to the skin.
There are three basic types of ultraviolet radiation:
·
UVA (long-wave UV)
·
UVB (sunburn UV)
·
UVC (short-wave UV)
Table 1 summarizes the general features of each type.
Table 1 |
|
Ultraviolet Radiation Type |
General Features |
Ultraviolet A radiation UVA,
long-wave UV) |
-not filtered out in the
atmosphere |
Ultraviolet B radiation |
-some filtered out in the
atmosphere by the ozone layer |
Ultraviolet C radiation |
-filtered out in the atmosphere by
the ozone layer before reaching earth |
How does sunlight affect the skin?
When ultraviolet radiation reaches the skin,
some radiation is reflected away from the surface. The remaining radiation is
scattered into the tissues just beneath the skin's surface. A fraction of this
radiation is absorbed by the skin's living cells.
Ultraviolet radiation absorbed by living cells
damages sensitive substances that influence the skin's normal growth and
appearance. Damage can result in:
·
sunburn
·
increased rate of
aging of the skin
·
skin cancer
Sunburn
Sunburn is the most familiar and immediate
effect of ultraviolet radiation on the skin. It is an inflammation caused by an
increase in blood-flow beneath the skin. The reaction is not normally
instantaneous, but reaches a bright red colour within 15 to 20 hours. The
condition can be very painful and sometimes causes peeling of the skin.
Brief intense exposure can cause severe sunburn in people who
are not accustomed to strong sunlight. There is evidence that this type of
exposure, as well as long-term exposures, might be linked to serious forms of
skin cancer later in life.
Increased Rate of
Aging of the Skin
Repeated exposure to the sun's ultraviolet radiation eventually
causes skin damage similar to the aging process. Patches of skin become thin
and less elastic, and develop blemishes, sun freckles, and wrinkles. These
changes may take many years of exposure but when they occur, the damage is
irreversible.
Skin Cancer
If exposure to sunlight continues for several
years, the damaged skin has an increased chance of developing one of the forms
of skin cancer. Exposure to ultraviolet radiation increases the risk of
developing these cancers (although it may not be the only cause of the
disease). While the exact relationship is not 100% defined, it appears that
intermittent (occasional) exposure and exposure during childhood and
adolescence are likely important predictors for basal cell carcinoma, and
cutaneous malignant melanoma. High levels of chronic exposure, such as working
outdoors, is more often associated with squamous cell tumours.
The following facts also link sunlight
exposure to skin cancer:
·
Most skin cancer
occurs in areas of skin most heavily exposed to sunlight (ears, forehead, arms,
etc).
·
Skin cancer among
people who are sensitive to sunlight is more common in regions with stronger
sunlight.
·
People with genetic
diseases that make them more sensitive to sunlight have a greater chance of
developing skin cancer.
·
Studies show that
ultraviolet radiation similar to sunlight causes skin cancer in animals.
What types of skin cancer are linked to
sunlight exposure?
Three different types of skin cancer are linked
to sunlight exposure:
·
basal cell cancer
·
squamous cell cancer
·
malignant melanoma
Basal Cell Cancer
Basal cell cancer is the most common of all cancers in North
America and Europe. It is usually found in areas of the skin exposed to
sunlight, but sometimes occurs in other areas as well. This type of skin cancer
appears as a raised, hard, red or red-grey, pearly wound often found on the
forehead, eyelids, cheeks, nose, and lips. Although there is always a chance it
could become serious, basal cell cancer usually does not spread. Most cases are
easily treated and cured.
Squamous Cell Cancer
Squamous cell cancer occurs most frequently on the skin exposed
to sunlight over long periods of time. As such, this type of skin cancer tends
to develop where maximum exposure to radiation occurs - forehead, cheeks, nose,
lower lip, and tops of the ears. It also usually develops in areas where the
skin has been damaged by the sun - areas with blemishes or sun freckles. The
blemishes develop into rough, scaly patches with small areas of open wound that
do not heal. They eventually grow into larger wounds with crusts. This type of
cancer can be removed with a good chance of total cure, if caught in time. It
is most dangerous if it occurs on mucous membranes such as on the lip.
Malignant Melanoma
Malignant melanoma, although rarer, is the
most serious of the skin cancers. It often shows itself as a mole or pigment
spot that begins to bleed, grow, or change its colour, shape or texture. It
usually spreads if not treated in the early stage. The exact nature of the
relationship between malignant melanoma and sun light is not completely clear.
However, brief intense exposure (intermittent exposure) to strong sunlight
appears to increase the risk of malignant melanoma in people who are not used
to strong sunlight. If caught early, malignant melanoma can be treated and
cured. If treatment is delayed, it is often fatal.
What factors affect a person's risk?
Four main factors influence the risk of skin
cancer:
·
skin pigment and
ability to tan
·
heredity
·
exposure to chemicals
·
amount of exposure to
sunlight
Skin Pigment and Ability
to Tan
Ultraviolet radiation from sunlight affects
everybody's skin to some extent, but the skin's response varies widely from
person to person. Peoples' sensitivity to the sun varies according to the
amount of pigment in the skin and the skin's ability to tan.
Ultraviolet radiation causes tanning in two
different ways: by immediate tanning and by delayed tanning. Immediate tanning
causes the skin to darken in response to UVA. This darkening begins during the
period of exposure, but fades within a few hours or days. The amount of tanning
increases according to the skin's natural darkness and previous amount of
tanning.
Delayed tanning occurs two to three days after
exposure to either UVA or UVB. It lasts from several weeks to months, and is
maintained by repeated exposure to sunlight. With delayed tanning, the skin
increases its production and distribution of dark pigment. The skin also
becomes thicker. These changes can follow sunburning or develop gradually over
a long period of repeated brief exposures to sunlight.
Some people burn easily after the first hour of sun exposure
following winter or any period away from the sun. Other people, especially
those with dark skin, rarely burn. This difference in reaction makes it
possible to classify skin into one of six different types (see Table 2).
Table
2 |
|||
Type |
Natural Skin Colour |
UV Sensitivity and Tendency to
Burn |
Skin Cancer Risk |
1 |
Very fair, pale white, often
freckled |
Highly sensitive. |
Greatest risk of skin cancer. |
2 |
Fair, white skin |
Very sensitive. |
High risk of skin cancer. |
3 |
Light brown |
Sensitive. |
High risk of skin cancer. |
4 |
Moderate brown |
Less sensitive. |
At risk of skin cancer. |
5 |
Dark brown |
Minimal sensitivity. |
Skin cancers are relatively rare,
but those that occur are often detected at a later, more dangerous stage.
Increased risk of low vitamin D levels. |
6 |
Deeply pigmented dark brown to
black |
Minimal sensitivity. |
Skin cancers are relatively rare,
but those that occur are often detected at a later, more dangerous stage.
Increased risk of low vitamin D levels. |
Table adapted from: SunSmart Victoria
(2012, Cancer Council Victoria), Australia
The risk of skin cancer from the sun generally follows the same
pattern. Darker skinned people have lower risk of sun-induced skin cancer. The
person most prone to skin cancer caused by sunlight tans poorly and suffers
sunburn easily. Frequent and/or intense sunburn in children with fair skin and
freckles has been linked to malignant melanoma later in life.
Heredity
For reasons not completely understood, people with Celtic
heritage (Irish, Scottish or Northern European) have increased risk of skin
cancer from the sun. Genetic diseases that affect the skin can also increase
the risk. For example, albinism, a genetic condition which prevents the
production of normal skin pigments, makes the skin sensitive to ultraviolet
light.
Exposure to Chemicals
Exposure to certain chemicals can increase the
skin's sensitivity to ultraviolet light through a process called
photosensitization. Examples of such chemicals include:
·
coal tar pitch and
petroleum products containing polycyclic aromatic hydrocarbons (PAHs)
·
certain printing
chemicals used in photosensitive printing processes
·
certain drugs and
antibiotics such as tetracyclines, sulfonamides, thiazide diuretics,
chlorpromazine, oral contraceptives
·
chemicals called
psoralens found naturally in certain plants, fruits and vegetables
Antibiotics must be taken internally before
the skin becomes sensitive to sunlight. (Check with your physician or
pharmacist is you suspect abnormal or severe reaction to sun exposure after
taking new medication.) However, simple skin contact with psoralens, which are
found in figs, parsnips, citrus plants, or mouldy celery, can make the skin
more susceptible to sunburns in some individuals.
Experimental studies show that chemicals called
"promoters" can increase the cancer-causing ability of ultraviolet
radiation. On the other hand, ultraviolet radiation itself can act as a
promoter. In particular, ultraviolet radiation (UVR) can increase the
cancer-causing ability of chemicals from coal tar and pitch.
Amount of Exposure to
Sunlight
The damaging effects of ultraviolet radiation
accumulate over the years. In general, the risk of developing skin cancer
increases with the amount of time spent under the sun and the intensity of
radiation. The intensity of radiation varies according to the season of the
year, time of day, geographic location (latitude), elevation above sea level,
reflection from surfaces (e.g., white sand or concrete, water, snow),
stratospheric ozone, clouds, and air pollution.
Recent studies have focused on the effects of
intermittent (short-term, occasional) sun exposure in comparison to chronic
(long-term) exposure. It appears that the type of exposure may influence the
type of cancer that develops. For example, intermittent solar exposure may be
an important factor leading to the onset of basal cell carcinoma of the skin.
Childhood sun exposure may also play an important part in the development of
these cancers later in adult life. The pattern for cutaneous melanoma is
similar to that for basal cell carcinoma.
In contrast, the relationship between squamous
cell carcinoma and solar UVR appears to be quite different. For squamous cell
tumours, high levels of chronic occupational sunlight exposure, especially in
the 10 years prior to diagnosis, results in an elevated risk for this cancer in
the highest exposure group.
What is the UV Index?
UV Index |
Description |
Sun Protection Actions |
|
0 - 2 |
Low |
·
Minimal sun
protection required for normal activity ·
Wear
sunglasses on bright days. If outside for more than one hour, cover up and
use sunscreen ·
Reflection
off snow can nearly double UV strength. Wear sunglasses and apply sunscreen |
|
3 - 5 |
Moderate |
·
Take
precautions - cover up, wear a hat, sunglasses and sunscreen especially if
you will be outside for 30 minutes or more ·
Look for
shade near midday when the sun is strongest |
|
6 - 7 |
High |
·
Protection
required - UV radiation damages the skin and can cause sunburn ·
Reduce time
in the sun between 11 a.m. and 4 p.m. and take full precautions - seek shade,
cover up, wear a hat, sunglasses and sunscreen |
|
8 - 10 |
Very High |
·
Extra
precautions required - unprotected skin will be damaged and can burn quickly ·
Avoid the sun
between 11 a.m. and 4 p.m. and take full precautions - seek shade, cover up,
wear a hat, sunglasses and sunscreen |
|
11+ |
Extreme |
·
Values of 11
or more are very rare in Canada. However, the UV Index can reach 14 or more
in the tropics and southern U.S. ·
Take full
precautions. Unprotected skin will be damaged and can burn in minutes. Avoid
the sun between 11 a.m. and 4 p.m., cover up, wear a hat, sunglasses and
sunscreen ·
White sand
and other bright surfaces reflect UV radiation and increase UV exposure |
What workers are at risk?
All outdoor workers potentially exposed to the
sun's ultraviolet radiation are at risk, including:
·
agricultural workers
·
farmers
·
horticultural workers
·
maintenance workers
·
pipeline workers
·
ranchers
·
athletes
·
fishermen
·
landscapers
·
military personnel
·
police
·
ski instructors
·
brick masons
·
gardeners
·
lifeguards
·
oilfield workers
·
postal carriers
·
sailors
·
construction workers
·
greenskeepers
·
loggers
·
open-pit miners
·
railroad track workers
·
surveyors
How can I reduce the risk of skin cancer from
sunlight?
Skin cancer is the result of decades of
exposure to the sun. It is important to be aware of the risks and take
precautions while under the sun from as early in life as possible. Approaches
to prevent skin cancer include:
·
reducing exposure to
sunlight
·
wearing protective
clothing
·
using sunscreens on
exposed skin
·
examining the skin
regularly for suspicious spots
In the winter time, it may be advisable to the above precautions
when exposed to sun for prolonged periods, especially in the presence of snow
or at high altitudes.
Reducing Exposure
Workers should avoid unnecessary exposure to
the sun, especially to the intense midday rays between 11:00 a.m. and 4:00 p.m.
during the summer. If possible, people should plan outdoor work for early
morning or late afternoon, and work in the shade as much as possible.
Umbrellas, buildings, trees, canopies, etc., can protect against the direct
rays from the sun. Work, and take breaks in the shade when ever possible. Set
up shade structures when shade is not available. In addition, water, white sand
or concrete, snow, and ice can reflect from around 10 percent to 85 percent of
the sun's ultraviolet radiation. Skin may require extra protection against
these indirect, reflected rays.
Workplaces can also rotate workers between site locations to
help reduce UV exposure.
Wearing Protective
Clothing and Sunglasses
The use of wide brim hats and clothes made from close-knit
fabric can protect the skin and scalp from ultraviolet radiation. Although
long-sleeved shirts and long-legged pants may not be comfortable in extremely
hot weather, they do help protect the skin. Not all clothing offers the same
protection. For example, a white cotton T-shirt may have an SPF of 7 while a
long-sleaved denim shirt has an estimated SPF of 1700. And some fabrics like
cotton lose about 50% of their SPF rating when they get wet. Workers should be
informed about different fabric characteristics that effect the transmission of
sunlight. Also wear wrap-around sunglasses that absorb UVA and UVB radiation.
Using Protective
Sunscreens
Workers should liberally apply protective
sunscreen on exposed skin 20 minutes before working in the sun, then reapply it
during the periods they spend under the sun, as directed by the manufacturer's
instructions (usually every two hours). Most sunscreens are colourless,
invisible, and cosmetically acceptable provided they do not stain clothing or
produce adverse skin reactions.
Sunscreens should be used in addition to, not
instead of, working in shade and wearing suitable clothing, hats, and
sunglasses. Sunscreens are not intended to extend the exposure time to
sunlight, but rather to reduce the effects of sunlight when people have to be
in the sun. The level of protection depends greatly on how the sunscreen is
applied.
A wide variety of sunscreens are available.
They all contain chemical ingredients that weaken (but do not eliminate) the
effects of ultraviolet radiation. The most widely used protective chemicals are
PABA (para-aminobenzoic acid) and closely related chemicals such as cinnamates,
salicylates, benzophenones, or anthranilates. Some sunscreens contain only one
of these protective chemicals while others may have two or more for greater
reliability. Products such as baby oil, cocoa butter, or skin oils that do not
have protective chemicals, do not protect against sunburn, skin aging, or skin
cancer.
Skin cancer develops primarily on areas of sun-exposed skin, including the scalp, face, lips, ears, neck, chest, arms and hands, and on the legs in women. But it can also form on areas that rarely see the light of day — your palms, beneath your fingernails or toenails, and your genital area.
Skin cancer affects people of all skin tones, including those with darker complexions. When melanoma occurs in people with dark skin tones, it's more likely to occur in areas not normally exposed to the sun, such as the palms of the hands and soles of the feet.
Basal cell carcinoma usually occurs in sun-exposed areas of your body, such as your neck or face.
Basal cell carcinoma may appear as:
Most often, squamous cell carcinoma occurs on sun-exposed areas of your body, such as your face, ears and hands. People with darker skin are more likely to develop squamous cell carcinoma on areas that aren't often exposed to the sun.
Squamous cell carcinoma may appear as:
Melanoma can develop anywhere on your body, in otherwise normal skin or in an existing mole that becomes cancerous. Melanoma most often appears on the face or the trunk of affected men. In women, this type of cancer most often develops on the lower legs. In both men and women, melanoma can occur on skin that hasn't been exposed to the sun.
Melanoma can affect people of any skin tone. In people with darker skin tones, melanoma tends to occur on the palms or soles, or under the fingernails or toenails.
Melanoma signs include:
Other, less common types of skin cancer include:
Kaposi sarcoma. This rare form of skin cancer develops in the skin's blood vessels and causes red or purple patches on the skin or mucous membranes.
Kaposi sarcoma mainly occurs in people with weakened immune systems, such as people with AIDS, and in people taking medications that suppress their natural immunity, such as people who've undergone organ transplants.
Other people with an increased risk of Kaposi sarcoma include young men living in Africa or older men of Italian or Eastern European Jewish heritage.
Make an appointment with your doctor if you notice any changes to your skin that worry you. Not all skin changes are caused by skin cancer. Your doctor will investigate your skin changes to determine a cause.